With a length of 3.7 kilometers (2.3 mi),[1] it begins at its intersection with PR-164 on the downtown Naranjito–Achiote line, and ends at its junction with PR-152 in Cedro Abajo barrio.

[2] Due to its rural characteristics, PR-810 consists of one lane per direction for its entire length.

It begins at PR-164 junction near downtown Naranjito and continues to the south through southwestern Achiote barrio, near to the western bank of the Río Guadiana.

[3] Before its current numerical designation, the entire length of PR-810 belonged to an original segment of PR-152 prior to its deviation along the eastern bank of the Guadiana River though Anones.

Those numerical designations correspond to the 1953 Puerto Rico highway renumbering, a process implemented by the Puerto Rico Department of Transportation and Public Works (Spanish: Departamento de Transportación y Obras Públicas) that increased the insular highway network to connect existing routes with different locations around Puerto Rico.