The Pulaski Expressway was to begin at an interchange with I-95 and the Betsy Ross Bridge in Northeast Philadelphia, where the road continues into New Jersey as Route 90.

The freeway was to continue north through residential and industrial areas before passing through Tacony Creek Park.

The routing had several alternatives including aligning with Adams Avenue (cutting through cemeteries or avoiding them), go through Tacony Creek Park, using the Reading Railroad spur east of Adams Avenue, or cutting through Simpson Memorial Park.

In 1975, the first two houses were demolished for the new freeway, and a group called United Communities Against the Pulaski Expressway erected a monument at the site that attacked Governor Milton Shapp and PennDOT.

[12] Vestiges of this extension can be seen from Interstate 95 in the form of stub ramps and the mainline coming to an abrupt end as a barricaded bridge.