North Key Largo is an unincorporated area and census-designated place (CDP) in Monroe County, Florida, United States.

Palo Alto Key is to the north, and the Atlantic Ocean is to the east.

[1] As of the census[3] of 2000, there were 1,049 people, 565 households, and 376 families living in the CDP.

29.7% of all households were made up of individuals, and 15.9% had someone living alone who was 65 years of age or older.

None of the families and 0.5% of the population were living below the poverty line, including no under eighteens and 0.8% of those over 64.