Pyrrocaine

The cogency of pyrrocaine is equivalent to lidocaine in blocking the motor nerve and sensory.

[1] In the 1960s it was most of the time used as a nerve blocker dental anesthetic and dentists recommended it due to its fast commencement.

[1] Pyrrocane has very similar side effects on blood pressure and heart rate compared to lidocaine.

[2] Selfsame as lidocaine, albeit interposing pyrrolidine for diethylamine.

Displacement of the remaining halogen by pyrrolidine (4) completed the synthesis of Pyrrocaine (5).

Synthesis: [ 3 ] Patents: [ 4 ] [ 5 ]