Queen of the Spiders is an adventure module for the Dungeons & Dragons fantasy role-playing game.

Together, the seven adventures form an integrated campaign that begins in the World of Greyhawk, continues underground into the Underdark, and concludes in the Demonweb Pits, the abyssal lair of the demonic goddess Lolth.

The larger campaign begins with T1–4, The Temple of Elemental Evil, continues on to A1–4, Scourge of the Slave Lords, and concludes with GDQ1–7.

A secret passage from this module leads deep into the earth, where the adventurers discover the true nature of the force behind the raids – the drow in the service of Lolth, the demoness.

The fourth module, Descent into the Depths of the Earth, is on a larger scale than the others, with a map covering many kilometres of a deep underground region, later known as the Underdark.

In the Underdark, there are many unique monsters previously unknown to surface adventurers, including the drow, which had been considered mythical.

Troglodytes, jermlaine and svirfneblin (deep gnomes) made their first appearances in D&D literature in this module.