The show typically consists of highlights, but major stories such as contract signings, trades or player retirements are also covered.

A unique trait of Quick Pitch is that in the highlights, they use the television or radio announcers' call of the game instead of the host commentating every play.

In previous years, this extra time had to be filled by long-form recorded segments due to the single-host format of the show.

While Watney and Ryan maintained their duties, Rizzo left to join the Los Angeles Dodgers broadcast team (though she later returned to MLB Network as the co-host of High Heat with Chris Russo).

Kelly Nash currently (2022) hosts Quick Pitch on weekends and occasional weekdays, with occasional fill-ins from Hersch as well as fellow NHL Network personalities Jackie Redmond, Erika Wachter, and Lauren Gardner (who joined the MLB Network in 2019 and is the current host of Off Base).

Alexa Datt (who also worked at NHL Network) also filled in occasionally until her departure in 2021 (when she joined Bally Sports Midwest).

In late July 2023, Marquee Sports reporter Taylor McGregor made her first appearance as a fill-in.