The Quinipissa (sometimes spelled Kinipissa in French sources) were an Indigenous people of the Southeastern Woodlands who were living on the lower Mississippi River, in present-day Louisiana, as reported by René-Robert Cavelier, Sieur de La Salle in 1682.
In 1682, La Salle encountered a group of Quinipissa living with the Koroa in a village on the western bank of the Mississippi River.
In 1700, the Bayagoula massacred both the Quinipissa and Mougoulacha, and they were not mentioned again by chroniclers of the time.
Albert Gatschet considered Quinipissa a Muskogean language Coast Choctaw ("Coast Chaʼhta") based on evidence that many peoples of this area spoke the lingua franca Mobilian Jargon and have names that appear to be exonyms of Mobilian Jargon or Muskogean origin.
However, a map by Nicolas de Fer states that all nations of this region spoke different languages and barely understood each other.