The economy is based on agriculture, cattle raising, services, public administration, and small transformation industries.

Natural and artificial pastures make up most of the land, on which there is large-scale cattle raising for beef and milk.

In tourism Lago do Sol Poente is a lake that attracts many visitors who can practice jet ski and motocross.

Cachoeira Sete Ilhas, in the Rio São Francisco, is a waterfall with seven islands that has exuberant tropical vegetation.

The written European history of Quirinópolis begins in 1832 with the arrival of João Cristóstomo de Oliveira, who was from Minas Gerais.

In 1879 the name was changed to Nossa Senhora da Abadia, later Rio Verde, and finally Quirinópolis honoring the builder of the first chapel, José Quirino Cardoso.