The Ministry of National Defense of the Republic of China (MND; Chinese: 中華民國國防部; pinyin: Zhōnghuá Mínguó Guófángbù) is the ministry of the Republic of China (Taiwan) responsible for all defense and military affairs of Taiwan and surrounding area.

It established a military occupation operation center in Taipei, Formosa in November 1945, following the Supreme Commander for the Allied Powers Douglas MacArthur's September 2, 1945 General Order No.

The 8-story main building was constructed at a cost of NT$15.8 billion, spreading over 19.5 hectares of area, which houses office buildings, dormitories and other facilities, such as post office, barbershop, sports center, conference hall and sport center to accommodate its 3,000 military personnel stationed there.

The compound also has eco-friendly features, such as stone walls, aluminum and low-emission exterior glass panels.

NT$5 billion (US$147 million) were allocated for the first five years of the program with an initial focus on information security and robotics, artificial intelligence, the internet of things and quantum computing.

Previously funding had been allocated through intermediaries with most going to military affiliated research organizations like National Chung-Shan Institute of Science and Technology (NCSIST).