In concrete terms: Any philosophical worldview is flawed if it stops at the physical level and fails to explain how meaning, values and intentionality can arise from that.
The conclusion is that our worldview does not need "extraneous trans-empirical connective support, but possesses in its own right a concatenated or continuous structure."
Empiricism is a theory of knowledge that emphasizes the role of experience, especially sensory perception, in the formation of ideas, while discounting a priori reasoning, intuition, or revelation.
Such a "thick" description of conscious experience was already part of William James' monumental work The Principles of Psychology in 1890, more than a decade before he first wrote about radical empiricism.
It differs notably from the traditional empiricist view of Locke and Hume, who see experience in terms of atoms like patches of color and soundwaves, which are in themselves meaningless and need to be interpreted by ratiocination before we can act upon them.