He played college football at South Carolina State and was signed by the Atlanta Falcons as an undrafted free agent in 2010.

He was also a member of the Denver Broncos, New Orleans Saints, Detroit Lions, and Buffalo Bills.

Bush was a restricted free agent after the 2013 season, and he signed an offer sheet with the Falcons that would have returned him to Atlanta for reported compensation of about $4.5 million for two years.

However, on April 7, 2014, the Saints exercised their right to match the Falcons' offer and bring Bush back to New Orleans.

The Rams were trailing by 3 in the two minute warning of the 4th quarter, and Bush intercepted Case Keenum, which sealed the victory for the Lions.