[3] In 1916, he published his first scientific paper (of more than 400) at the age of nineteen in the Journal of the American Chemical Society.
Wyckoff continued working in X-ray crystallography and wrote several books about the topic.
Wyckoff's 1922 book, The Analytical Expression of the Results of the Theory of Space Groups, contained tables with the positional coordinates, both general and special, permitted by the symmetry elements.
While there, he photographed the growth of living cells using ultraviolet light[4] and determined the structure of urea.
[5] In 1959, appalled by growing bureaucracy at the NIH, he took the job of professor of microbiology and physics at the University of Arizona in Tucson, where he was forced to retire at the age of 80.