[1] The center tells a story of the cultural, natural, and scientific history of the Hanford Reach and Columbia Basin area, as well as promoting tourism.

[2] The Columbia River Exhibition of History, Science, and Technology (CREHST) was the predecessor that transitioned into what is now the Hanford Reach Interpretive Center.

Gallery two presents the story of the Hanford Site's early days and its role in the Manhattan Project.

Educational activities are offered by the center, from camps for kids to current environmental forums, and the museum hosts off site tours to several local areas.

[4] The Reach has a 14,000 square foot ground floor which contains the galleries, rotating exhibit, a great hall, and a store.