Samuel Francis Smith first read his poem "America" at BHCC; it was later set to music and became known as "My Country Tis of Thee."
Former Boston Mayor Thomas Menino and Massachusetts State Representative Angelo Scaccia are both longtime Readville residents.
In the early part of the 20th century, a prominent harness racing facility called Readville Trotting Park was located in the neighborhood.
Readville was also home to the massive New York, New Haven & Hartford Railroad Locomotive and Car Shops, which closed in 1960.
Today, the CSX Railroad operates a portion of the Readville Freight Yard along Prescott Street .The MBTA Commuter Rail has a passenger car facility for light maintenance and servicing just outside Wolcott Square.
Amtrak's Northeast Corridor runs through Readville on trackage shared with MBTA Commuter and CSX freight operations.