Located in a 1/4-mile-wide valley with low streambanks, the site was ideal for ship building in a region geologically most often characterized by steep-plunging relatively inaccessible banks — wide enough to launch and float several large boats, and indeed steamboats after 1811, and slow-moving enough to provide good docks and parking places while craft were outfitting.

Flatboat construction is documented at the site from 1782, and the Braddock Expedition established a supply base (blockhouse) on the stream's south bank which the French destroyed after first taking Fort Necessity in 1754.

Nestled in the foothills on the west side of the mountains, Brownsville was a gateway funneling settlers to the Ohio Country, the lands of the Louisiana Territory, and did so until well after 1853, when railroads reached the Missouri River at Kanesville, Iowa (one Emigrant Trails destination of the town's flatboats), the far west and the Oregon Country —for the town astride the shortest, if not the easiest, land route across the great barrier to east-west traffic presented by the Allegheny Mountains.

From a post at present-day Cumberland, Maryland, the company began to construct an 80-mile (130 km) wagon road to the Monongahela River[7] employing a Delaware Indian chief named Nemacolin and a party of settlers headed by Capt.

The river crossing and flats at Redstone Creek, the earliest point and shortest distance the choices a wagon road descent could follow (later in the war, fortified as Fort Burd, now Brownsville) was one of several possible destinations.