Refuge is an unincorporated community located in Washington County, Mississippi, United States.

[1] Refuge Landing was located west of the settlement, directly on the Mississippi River.

[2][3] Francis Griffin purchased land in 1831 on a high ridge bordering the Mississippi River where he established "Refuge Plantation".

[5] The Refuge Plantation House, shaded by oak trees and protected from the river by a levee system, was erected with a view of the river, and remains today one of the best examples of a mid-nineteenth-century plantation house in Washington County.

[7] In 2010, the Greenville Bridge was opened connecting Refuge with Shives, Arkansas.