Wayside is an unincorporated community in Washington County, Mississippi, United States.

Wayside is located on Mississippi Highway 1 approximately 8 mi (13 km) south of Greenville.

[5] Wayside was originally located directly on the Mississippi River at the eastern end of "American Bend", and the early settlement had a steamboat landing.

[6][7] A branch of the Louisville, New Orleans and Texas Railway, completed in the late 1880s, passed through Wayside.

[8] On October 9, 2009, a tornado destroyed three mobile homes, damaged 16 houses and knocked down trees.