Remnant cholesterol

[1][2][3] Elevated remnant cholesterol is associated with increased risk of atherosclerotic cardiovascular disease and stroke.

[6] Remnant cholesterol corresponds to all cholesterol not found in high-density lipoprotein (HDL-C) and low-density lipoprotein (LDL-C).

It is calculated as total cholesterol minus HDL-C and LDL-C.[7] Elevated remnant cholesterol is associated with an increased risk of atherosclerotic cardiovascular disease, chronic inflammation, myocardial infarction and stroke.

[14] Although remnant cholesterol tends to be higher in people who are overweight (high body mass index), normal-weight persons with high remnant cholesterol tend to have a higher risk of myocardial infarction.

[15] Vupanorsen, an ANGPTL3 inhibitor has been shown to lower remnant cholesterol up to 59%.