Ripley is a city in Tippah County, Mississippi, United States.

W.C. Falkner's exploits in and around Ripley served as the model for Faulkner's character of Colonel John Sartoris.

As of the 2020 United States Census, there were 5,462 people, 1,735 households, and 1,100 families residing in the city.

30.5% of all households were made up of individuals, and 14.4% had someone living alone who was 65 years of age or older.

The City of Ripley is served by the South Tippah School District.

It started around the turn of the 20th century at the old square but is now held south of Ripley along Highway 15 across from the Tippah County Fair Grounds.

It has seen publicity by various news channels over the years for its tolerance of a controversial live animal market housed at the back edge of the trading grounds.