Moore played in the NFL as a wide receiver with the New York Jets from 1990 to 1994 and the Arizona Cardinals from 1995 to 2001.

In the 1997 season Moore caught 97 receptions for 1,584 yards and 8 touchdowns and en route to an All-Pro selection.

In January 2010, Moore was hired by Doug Marrone as the wide receivers coach at his alma mater, Syracuse University.

[4] On February 6, 2014, Moore was added to the Buffalo Bills staff as the receivers coach.

On January 29, 2018, Moore was hired as the wide receivers coach for the Tennessee Titans.