[6] After redshirting his first year in Philadelphia, Anderson saw time on special teams during his redshirt-freshman season and practiced primarily as a defensive back.

[14] Anderson entered training camp competing against Jalin Marshall, Chandler Worthy, Jeremy Ross, and Charone Peake to be the Jets' fifth wide receiver.

[15] He went on to lead all players in the 2016 pre-season in receiving yards with 264, and also had 13 catches and three touchdowns, which helped him earn a spot on the Jets' final 53-man roster and become their fifth wide receiver entering the regular season, behind Brandon Marshall, Eric Decker, Quincy Enunwa, and Jalin Marshall.

[16] He made his professional regular season debut in the Jets' season-opening 23–22 loss to the Cincinnati Bengals.

[19] Following Eric Decker's season-ending injury on October 12, 2016, Anderson became Jets' starting slot receiver.

[20] On December 5, 2016, he made four receptions for 61 yards and caught his first career touchdown on a 40-yard pass from Bryce Petty.

[28] Prior to the final play in the fourth quarter, Anderson threw his helmet in rage, frustrated that he wasn't getting enough targets, which drew an unsportsmanlike conduct penalty.

[38] During Week 16 against the Green Bay Packers, Anderson finished with 140 receiving yards and a touchdown as the Jets lost 38–44 in overtime.

[41] During Week 6 against the Dallas Cowboys, Anderson finished with five catches for 125 yards, including a 92-yard touchdown as the Jets won 24–22.

Anderson finished the game with six catches for 115 receiving yards and a touchdown from former Jets' teammate Teddy Bridgewater as the Panthers lost 30–34.

[46] During Week 2 against the Tampa Bay Buccaneers, Anderson finished with nine receptions for 109 receiving yards as the Panthers lost 17–31.

[48] In Week 12 against the Minnesota Vikings, Anderson recorded 4 catches for 94 yards, including a 41-yard touchdown reception, during the 28–27 loss.

[50] On August 24, 2021, Anderson re-signed with the Panthers on a two-year contract extension worth $29.5 million, which extended through the 2023 season.

[61][62] On September 24, 2023, while the Dolphins led the Broncos 56–13, Chosen, who had been a practice squad activation that day, caught a 68-yard pass from Mike White that he ran in for a touchdown.

[70] He was released by the Dolphins on September 17 after appearing in two regular season games,[71] finishing with one reception for five yards.