The Roman Catholic Diocese of Ciudad del Este (Latin: Dioecesis Urbis Orientalis) is a diocese of the Roman Catholic Church based in the city of Ciudad del Este, in the Ecclesiastical Province of Asunción in Paraguay.

On July 10, 1993, the territorial prelature was established as the Diocese of Alto Paraná.

[1] In 2014, Pope Francis dismissed the diocese's bishop, Rogelio Ricardo Livieres Plano, due to Livieres's alleged promotion of a diocesan priest who had been accused of the sexual abuse of a minor while serving in the United States.

Since then, accusations of major financial mismanagement of the finances of the diocese by Livieres have also surfaced, with the diocese reportedly close to a million United States dollars in debt.

This article on a Roman Catholic diocese in Paraguay is a stub.