The district includes the majority of the City of Rome.
It also includes portions of the following towns: Annsville, Lee, Verona, and Western.
The Rome school district includes the census-designated places of Lake Delta and Westernville.
[1] In 2019 the board of trustees extended the contract of superintendent Peter C. Blake by five years.
[2] In 2023, Mike Jaquays of the Rome Daily Sentinel wrote that the board of trustees "is not currently planning to renew" the contract of Blake.