She is a Professor of Neurobiology at Harvard Medical School and the Dana Farber Cancer Institute.,[1] and the Dean for Graduate Education at Harvard Medical School [2] Segal's work employs modern methods of cell and molecular biology to study the development of the mammalian brain with the goal of understanding how disruption of this normal process leads to the formation of brain malignancies.
She performed her doctoral dissertation research in the laboratory of David Luck, and her residency training in neurology in the Harvard affiliated hospitals in the Longwood Medical Area.
Segal completed postdoctoral research in molecular neuroscience in the laboratories of Ronald McKay and Charles Stiles.
Segal has also revealed a role for the local translation of select mRNAs at synapses to promote neural circuit survival and function.
She has mentored numerous graduate students and post-doctoral fellows, and serves as a faculty advisor for the Harvard Women in Neuroscience program.