After passing through several hands undeveloped, the mortgagee, The Sydney Land Bank and Financial Agency Co came into possession of it and subdivided the whole area into 38 allotments of 1–4 hectares (2–10 acres) in 1893 and was called the "Pymble View Estate.

"[1] During the turn of the century the more accessible areas attracted the attention of the developing middle class who were seeking property suitable for large houses and generous gardens in bushland settings.

[1] The gazettal of the Cumberland County Plan in 1951 led to the promoting of neighbourhood areas whilst retaining open space and green belts.

This planning scheme led to a new wave of developers and middle class professionals who were attracted to the bushland settings and vistas for architect-designed homes.

[4][1] However the garden that evolved around one of Australia's iconic prototypical modernist houses became an expression of the recent immigrant Rose Seidler's personal creativity.

Mrs Seidler particularly delighted in growing plants that she could not possibly have grown in Vienna or in England: frangipani (Plumeria rubra), oranges, port wine magnolia (Michelia figo) and Queensland firewheel tree (Stenocarpus sinuatus).

The resident gardening of Rose Seidler permeates the site and subtlety infiltrates both the native bushland and the modern landscaping.

The house is constructed of four basic materials; natural bush stone, reinforced concrete, timber and glass.

[1] Built in 1949–1950 in the International modernist style, it was futuristic and modern for Australia at that time, and is an outstanding example of mid-century-modern domestic architecture.

In 1948, the site had been used to mine pottery clay,[7] and was considered very remote - being at the end of a dirt road through market gardens.

[9][1] As at 8 December 2008, Rose Seidler House is historically significant as a resource to demonstrate the many features of Modernist art, architecture and design theory and practice.

The house incorporates many examples of modern domestic technology and commercial products which were introduced into Australia at this time.

[10][1] Rose Seidler House was listed on the New South Wales State Heritage Register on 2 April 1999 having satisfied the following criteria.

Rose Seidler House is historically significant as a resource to demonstrate the many features of Modernist art, architecture and design theory and practice.

[10][1] The place is important in demonstrating aesthetic characteristics and/or a high degree of creative or technical achievement in New South Wales.

Rose Seidler House contains intact contents of the late 1940s furniture by such renown designers as Eames, Saarin and Hardoy.

The house incorporates many examples of modern domestic technology and commercial products that demonstrate the introduction of electric appliances, labour saving devices, materials, fittings and storage systems into Australia.