The embassy of the Netherlands in Ghana has a long history, dating back to the period immediately following the cession of the Dutch Gold Coast to the United Kingdom in April 1872.

Apart from the regular diplomatic duties, the agents were also responsible for paying pensions to former employees of the colonial administration and to the African veterans of the Royal Netherlands East Indies Army.

Hamel subsequently appointed the French merchant Arthur Brun as honorary consul at Elmina and left the Gold Coast.

The Ghanaian economy is still largely dependent on the production and export of two primary goods, cocoa and gold, although the recent discovery of oil should help diversify both activities and sources of revenue.

There are programmes that aim to promote trade and development, such as ORIO, Private Sector Investment (PSI), 2xplore, and Matchmaking Facility (MMF).