[1] Roza Papo studied at the School of Medicine in Zagreb and worked as physician in Sarajevo, Begov Han and Olovo before the outbreak of the Second World War.
[2] Following the invasion of Yugoslavia by Nazi Germany in 1941, Papo made contact with the Yugoslav Partisans in Ozren and started aiding them.
[2] Jews throughout Europe joined resistance movements in an attempt to survive, but Papo's decision was also motivated by patriotism.
As an officer, Papo served directly under Josip Broz Tito, the leader of the yugoslav resistance.
She is credited with introducing new diagnostic methods, primarily liver biopsies, as well as the introduction of precise diagnosis of viral hepatitis and hyperbilirubinemia, as well as tuberculosis and purulent meningitis.