Lindsay was born in Creswick, Victoria,[1] the seventh child and second daughter of Robert and Jane Lindsay, and lived in Melbourne from the age of 16 with her brother Percy while studying at the National Gallery of Victoria School.

Lindsay drew occasionally for The Bulletin and illustrated William Moore's Studio Sketches (1906) and designed posters and certificates including the Certificate First Class and a prize-winning poster for the Australian Exhibition of Women’s Work, in 1907.

[3] She was described by art critic Haldane MacFall as "the most remarkable woman in the pen-line now living" in his History of Painting.

In 1912, she contributed illustrations to the book Epigrams of Eve by child welfare advocate and journalist Sophie Irene Loeb.

After World War I she visited relations in Ireland and died during the Spanish flu pandemic.