[1] In 2016, his senior year, he compiled a 1.91 ERA while batting .415, leading Basic to a state championship and earning a spot on the Nevada All-State team.

[5][6] He spent that summer playing in the Cape Cod Baseball League for the Yarmouth–Dennis Red Sox with whom he was named an All-Star.

[18] After eight starts in which he pitched to a 4–1 record with a 2.52 ERA and 59 strikeouts over 39+1⁄3 innings, he was promoted to the Amarillo Sod Poodles of the Double-A Central.

[23] He made his MLB debut that night as the club's starting pitcher versus the San Diego Padres, throwing seven scoreless innings while striking out seven batters and walking zero in a 5-0 Diamondbacks win.

[25] On August 13, 2023, Ryne Nelson was optioned back to the Reno Aces to make room for Bryce Jarvis's debut and improve his pitching, with a 5.47 ERA in 24 starts before demotion.