São Miguel do Passa Quatro is a municipality in central Goiás state, Brazil.

São Miguel is located in the Pires do Rio Microregion, at a distance of 112 kilometers from the state capital of Goiânia.

Highway connections from Goiânia are made by BR-352 / Bela Vista de Goiás / Cristianópolis / GO-139.

It has boundaries with Bela Vista de Goiás, Cristianópolis, Silvânia and Vianópolis.

The economy is based on subsistence agriculture, cattle raising, services, public administration, and small transformation industries.