[5][6][7] The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane.

The Sec61 complex forms a transmembrane channel where proteins are translocated across and integrated into the ER membrane.

This complex consists of three membrane proteins- alpha, beta, and gamma.

Alternatively spliced transcript variants encoding the same protein have been identified.

This article on a gene on human chromosome 7 is a stub.