This protein may be involved in regulating cell shape in certain tissues.

Mutations in this gene have been shown to cause heterotaxy.

[8] A similar protein in mice is required for proper neurulation,[5][7] eye,[9] and gut development.

[10][11] This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 4 is a stub.