The town of Sabina was laid out by Warren Sabin, after whom it was named, in 1830, on land originally entered by P. Neville.

The original plat of the town was recorded on December 6, 1830, and contained thirty-seven lots.

Once inhabited by Adenan and Hopewellian peoples, the district is listed on the National Register of Historic Places.

[7] Sabina is located along Routes 22 and 3 about ten miles east of Wilmington, the county seat.

It is also located within an hour's drive of the Columbus, Dayton, and Cincinnati metro areas.

Clinton-Fayette Friendship Trail starts at Melvin road and continues through Sabina ending at Borum RD.

The Sabina Park contains a shelter house with stage, playground equipment including wheelchair accessible swings, and a walking path.

This hospital operates the Sabina Health Center located east of town.

As well, Fayette County Memorial Hospital is located twelve miles east in Washington Court House.

Students in portions of the Fayette County area of Sabina attend Miami Trace High School.

A few Sabina area students also attend Greeneview High School in nearby Jamestown, Ohio.