Sabinene

It is isolated from the essential oils of a variety of plants including Marjoram,[2] holm oak (Quercus ilex) and Norway spruce (Picea abies).

Sabinene is one of the chemical compounds that contributes to the spiciness of black pepper and is a major constituent of carrot seed oil.

[4] It is biosynthesized from the common terpenoid precursor, geranyl pyrophosphate (GPP) that undergoes polycyclization catalyzed by sabinene synthase (SabS).

The starter units, IPP and DMAPP, can be synthesized from either the mevalonate (MVA) or the methylerythritol 4-phosphate (MEP) pathway.

Sabinene synthase (SabS) then catalyzes the ionization and isomerization of GPP to form 3R-linalyl pyrophosphate.

Sabinene
Sabinene
With the biosynthesis catalyzed by sabinene synthase, the precursor, geranyl pyrophosphate, undergoes isomerization and cyclization to form sabinene. [ 4 ] [ 6 ]