The 49er FX competition of the sailing events at the 2023 Pan American Games in Santiago was held from October 28 to November 3 at the Cofradia Nautica del Pacifico.

Points were assigned based on the finishing position in each race (1 for first, 2 for second, etc.).

The team with the lowest total score won.

The defending champions, Martine Grael and Kahena Kunze from Brazil, won the event.

Alexandra Ten Hove and Mariah Millen from Canada were the second, and Stephanie Roble and Maggie Shea from the United States won the bronze medal.