Argentina is scheduled to compete at the 2023 Pan American Games in Santiago, Chile from October 20 to November 5, 2023.

On 5 October 2023, the Argentine Olympic Committee officially named the team of 508 athletes (268 men and 240 women) competing in 38 sports (e-sports total of 14 is not included).

[1] Rugby sevens athlete Marcos Moneta and kayaker Sabrina Ameghino were the country's flagbearers during the opening ceremony.

[2] Volleyball athlete Facundo Conte and fencer Clara Di Tella were the country's flagbearers during the closing ceremony.

Argentina qualified a male archer in individual compound by winning the 2022 South American Games.

Argentina also qualified a male archer in individual recurve during the 2022 Pan American Archery Championships.

[25] Dante Cerquetti and Candela Espinosa Veloso also qualified after each winning a gold medal at the 2021 Junior Pan American Games in Cali, Colombia.

Argentina qualified a team of ten gymnasts in artistic (five men and five women) at the 2023 Pan American Championships.

[32] Argentina qualified a women's team (of 14 athletes) by winning the 2021 Junior Pan American Games.

[34] Mixed Argentina qualified a team of 6 karatekas (three men and three women) at the 2022 South American Games.

[42][43] Qualification Legend: FA=Final A (medal); FB=Final B (non-medal); SA/B=Semifinals A/B; R=Repechage Argentina qualified a men's team (of 12 athletes) after winning the 2022 South American Games.

Speed Boulder & lead Argentina qualified a male team of 3 athletes through the 2022 South American Games.

[54] Argentina qualified a full team of six athletes (three men and three women) through the 2022 South American Games.

[58][59] Argentina qualified a team of four triathletes (two men and two women) after finishing fifth at the 2023 Pan American Mixed Relays Championship.