Saint-Ghislain Abbey (French: Abbaye de Saint-Ghislain) was a monastery founded by Saint Ghislain around 650, located in Wallonia on the Haine (Hainaut, Belgium).

It became a Benedictine monastery around 940, when reformed by Gérard of Brogne, and was suppressed in 1796.

On 2 June 965, Otto I, Holy Roman Emperor, confirmed Godfrey of Lower Lotharingia's gift to the abbey of 18 mansi of land in Villers-Saint-Ghislain.

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