Sakaguchi test

The Sakaguchi test is a chemical test used to detect presence of arginine in proteins.

It is named after the Japanese food scientist and organic chemist, Shoyo Sakaguchi (1900–1995) who described the test in 1925.

[1] The Sakaguchi reagent used in the test consists of 1-Naphthol and a drop of sodium hypobromite.

The guanidino (–C group in arginine reacts with the Sakaguchi reagent to form a red-coloured complex.

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