Salidroside

Salidroside (rhodioloside) is a glucoside of tyrosol found in the plant Rhodiola rosea.

[1] It has been studied, along with rosavin, as one of the potential compounds responsible for the putative antidepressant and anxiolytic actions of this plant.

Salidroside was shown to improve glucose homeostasis and alleviate diabetic retinopathy in obese mice.

[5][6] The antioxidant, anti-inflammatory and neuroprotective effects of salidroside have also been reported.

[10] Rhodiola contains a pyridoxal phosphate-dependent 4-hydroxyphenylacetaldehyde (4-HPAA) synthase that converts tyrosine to 4-HPAA, which is further reduced to tyrosol by 4-HPAA reductase.