Salisbury High School is a public high school located in Salisbury Township, Pennsylvania, in the Lehigh Valley region of eastern Pennsylvania.

Salisbury participates in the Colonial League of the Pennsylvania Interscholastic Athletic Association's District XI.

The Colonial League includes Lehigh Valley high schools deemed too small to participate in the East Penn Conference.

The school fields teams in most major sports, including boys baseball, boys and girls basketball, boys tennis, cheerleading, girls field hockey, girls softball, football, soccer, rifle, wrestling, and track and field.

[4] Salisbury has the Colonial League titles in Basketball and Baseball.