Salt Creek is a 30-mile (48 km) tributary of the Middle Fork Willamette River in Lane County in the U.S. state of Oregon.

It proceeds generally south, through Gold Lake, to Route 58, which it then follows mainly northwest for about 26 miles (42 km) to its mouth at the Middle Fork Willamette River just below Hills Creek Dam.

[6][7][8] At Salt Creek Falls—roughly 4 miles (6.4 km) west of Willamette Pass and a little more than 22 miles (35 km) upstream from the mouth[7][9]—the stream plunges 286 feet (87 m),[10] discharging an average of 50,000 U.S. gallons (190,000 L) of water per minute, or 111 cubic feet per second (3.1 m3/s).

[11] Below the falls, the creek enters a narrow canyon shaped by glaciation and basaltic lava flows from higher in the Cascades.

Bull trout formerly inhabited Salt Creek until damage to habitat throughout the Willamette River basin, such as dams, reduced their numbers in the Willamette's watershed.