Saltlick Creek is a tributary of the Little Kanawha River, 17.7 miles (28.5 km) long,[3] located in central West Virginia in the United States.

Saltlick Creek flows for its entire length in Braxton County.

It rises approximately 2 miles (3.2 km) south of Flatwoods and flows generally northward, through the communities of Corley, Rollyson, and Gem to its mouth at the Little Kanawha River in Burnsville.

Downstream of Rollyson, the creek is paralleled by West Virginia Route 5.

[5] According to the West Virginia Department of Environmental Protection, approximately 80% of the Saltlick Creek watershed is forested, mostly deciduous.