Born and raised in Ventura, California, Whitcomb played soccer as a child before taking up basketball at age 12.

She also helped her team win three Channel League titles as a sophomore, junior and senior.

She led the team with an 81.0 free-throw shooting percentage (17-for-21), was fourth on the squad with 15 three-pointers made, and averaged 4.3 points and 1.6 rebounds per game.

[3] As a sophomore in 2007–08, Whitcomb's role on the team increased dramatically as she appeared in all 31 games and received 30 starting assignments.

She averaged a career-best 13.0 points per game, set a personal high with 175 rebounds, and was named Pac-10 Player of the Week on December 28, 2009.

[3][5] In her four-year career at Washington, Whitcomb scored 1,205 points, a mark that ranks 15th all-time in the program's history.

[6] After going undrafted in the 2010 WNBA draft, Whitcomb signed a training camp contract with the Chicago Sky on April 25, 2010.

[14] On May 26, she scored a career-high 22 points and hit six three-pointers in 15 minutes off the bench in an 87–81 win over the New York Liberty.

[24] On August 12, 2020, she tied her career high for 3-pointers in a game with six to finish with a season-high 20 points in a 100–63 win over the Atlanta Dream.

[25] After appearing in all three games of the Storm's 3–0 semifinal series sweep over the Minnesota Lynx,[24][26] she left the WNBA bubble in Bradenton, Florida, and returned to Perth, Australia, to be with her wife for the birth of their first child.

[27][28] The Storm went on to defeat the Las Vegas Aces 3–0 in the Finals to garner Whitcomb her second WNBA championship.

[29] For the season, Whitcomb led Seattle's reserves with a career-high 8.1 points per game alongside 2.3 rebounds, 2.0 assists and 16.5 minutes.

[27] On February 10, 2021, Whitcomb was acquired by the New York Liberty via sign-and-trade in exchange for the rights to Stephanie Talbot.

[33] On February 3, 2023, Whitcomb signed a two-year deal with the Seattle Storm, returning to the franchise for a second stint.

[41] Whitcomb considered signing in Switzerland for the 2010–11 season but the perceived lack of strong competition to prepare her to break into the WNBA ultimately led her to initially end her playing career.

[6] In June 2011, Whitcomb launched her pro basketball career by signing with ChemCats Chemnitz of the Damen-Basketball-Bundesliga (DBBL) in Germany.

[54] Whitcomb initially signed with French team ESB Villeneuve-d'Ascq for the 2021–22 season,[55] but changes in family circumstance saw her return to Perth instead.

[32][56] Following the 2012–13 season in Germany, Whitcomb began travelling through Europe hoping another team would sign her when she received a call to come to Australia to play for the Rockingham Flames in the State Basketball League (SBL).

[61] Her 41 points in the 68–63 win over the Willetton Tigers earned her back-to-back grand final MVPs as the Flames claimed their second consecutive championship.

[58] In her fourth season with the Flames in 2016, Whitcomb once again earned All-Star Five honors[65] and averaged 24.7 points, 8.4 rebounds, 3.4 assists and 2.8 steals in 25 games.

[58] In 2018, Whitcomb had a three-week stint with the Willetton Tigers and subsequently won three straight SBL Player of the Week awards.

She finished the season with averages of 24.1 points, 5.2 rebounds, 3.9 assists and 2.6 steals per game, while shooting 41 per cent from beyond the arc.

[104][105] However, on November 4, 2020, she opted out of joining the Lynx for the WNBL Hub season in Queensland in order to be alongside her wife in Perth for the birth of their first child.

[109] In game one of the semi-finals against the University of Canberra Capitals, Whitcomb scored a game-high 20 points with 11 rebounds in a 91–77 win.

[118] On December 29, 2023, she scored a season-high 26 points while playing all 45 minutes of the Fire's overtime loss to the Sydney Flames.

[123] On December 5, she recorded the first triple-double of her WNBL career with 16 points, 13 rebounds and 10 assists in a 72–66 win over the Perth Lynx, helping the Spirit remain undefeated to start the season.

[131] On February 1, 2018, Whitcomb was naturalized at a ceremony in Perth before flying to Italy the next day for the Opals' training camp.

[133] In September 2018, Whitcomb debuted with the Opals at the FIBA World Cup after she replaced the injured Leilani Mitchell.

[135][136] She helped the Opals reach the bronze medal match, where they defeated South Korea 88–58 behind Whitcomb's 15 points, nine rebounds and eight assists.

[140] Stats current through end of 2024 season Whitcomb is the daughter of Jan and Sander, and has an older brother, Jason.