Samo Phlue (Thai: สมอพลือ, pronounced [sā.mɔ̌ː pʰlɯ̄ː]) is a tambon (sub-district) of Ban Lat District, Phetchaburi Province, western Thailand.

Neighboring sub-districts are (from the north clockwise): Ton Mamuang and Pho Rai Wan of Mueang Phetchaburi District and Tha Sen and Ban Lat of Ban Lat District.

[1] In the Ayutthaya period, Samo Phlue was the residence of the royal Brahmin, with settlements around 1457 (coincides King Trailok's reign).

Brahmins were the gentry of their day, the ancestors of many important people in Thai history, for example, Princess Aphainuchit, mother of Prince Thammathibet; Princess Phiphit Montri, mother of two Ayutthaya kings, Uthumphon and Ekkathat; the royal poet of the early-Rattanakosin period, Sunthon Phu.

[2] The Phetchaburi River flowing through Wat Tha Chaisiri temple is still believed to be "holy water", thus used in the coronation ceremony of the Thai monarchs of each period.