Samuel Clemens High School is a public high school in Schertz, Texas, United States.

In 1961 the school district was established and in 1967 Universal City was annexed into the district, formally becoming SCUC ISD.

A decision was made to rename the school, however all the band jackets and other uniforms featured the letters SC for "Schertz-Cibolo," and it would have proved cost prohibitive to change it.

A contest was held to name the school using those same initials of SC, and Samuel Clemens was the winner.

Samuel Clemens is better known by the pen name Mark Twain.