Samuel Jones Wilkin (December 17, 1793 – March 11, 1866) was a U.S. representative from New York, son of James W. Wilkin.

Born in Goshen, New York, Wilkin graduated from Princeton College in 1812.

He was a member of the New York State Assembly (Orange Co.) in 1824 and 1825.

He was an unsuccessful Whig candidate for election in 1844 as Lieutenant Governor of New York.

His son, Alexander Wilkin, died in the Civil War.