Lowery worked in wool mills starting as a teenager.
He ran a furnishing goods' store in Utica from about 1855 to 1860, and was engaged in the wool business for about 30 years after that, owning a couple of factories.
He was chairman of the committees on state prisons and banks while in the Senate.
He died in April 1912 in Utica, New York; and was buried at the Sauquoit Valley Cemetery in Clayville.
Lowery was a Presbyterian, and a trustee at Utica's Westminster Church.