Born at Exeter on 16 December 1714, he was the fourth son of Robert Walker of Withycombe Raleigh near Exmouth, Devon, by his wife Margaret, daughter of Richard Hall, rector of St. Edmund and All Hallows, Exeter; Robert Walker (1699–1789), his elder brother, made manuscript collections for the history of Cornwall and Devon, which went to Sir Thomas Phillipps.
[1] In 1737 Walker was appointed curate of Doddiscombe Leigh, near Exeter, but resigned his position in August 1738 to accompany Lord Rolle's youngest brother to France as tutor.
In 1746 he resigned the vicarage, which he had only held in trust, and was appointed curate of Truro and vicar of Talland.
[1] In 1754 Walker tried to set up religious society bound by rules of conduct.
[4] Walker died unmarried on 19 July 1761 at Blackheath, at the house of William Legge, 2nd Earl of Dartmouth, a supporter.