In May 2022, the parish held an exhibition of biographical and iconographic works related to San Felice da Cantalice, a friend of Philip Neri.

On 14 November 1929, the Italian Marquis Achilles Muti-Bussi donated the land to the Vicariate of Rome as a gesture of goodwill for its impoverished peasants living nearby, many from the Lazio countryside.

On 1 January 1970, on the occasion of the World Day of Peace, Pope Paul VI blessed the apse of the church in a ceremony televised live by RAI.

The church is decorated with works of the Franciscan Capuchin artist Ugolino da Belluno, which include the Madonna and Child with Saint Felix in the apse and the Appearance of angels and Jesus in a vision of St Francis in the transept.

At the time, the fresco was heavily criticized for its polychrome colours, the poor natural lighting, and the manner in which it was painted on the wall of 480 square meters.

The fresco in the apse features the Madonna as Virgin of the Flowers, wearing a robe of lilies while handing down the Child Jesus to Saint Felix, hooded and prostrate.