The San Francisco Health Department closed Chinese businesses and subsequently burned parts of Chinatown.

Health officials, dissatisfied with the ruling, ostracized and isolated Chinatown and all its inhabitants, because of their fears of the plague spreading.

In addition, any obtained tissues from suspicious causes of death would directly be sent to the Public Health Service Laboratory in San Francisco to help identify and eradicate the infection.

A comprehensive medical center, ZSFG serves approximately 100,000 patients per year and provides 20 percent of the city’s inpatient care.

[7] In fulfilling the San Francisco Department of Public Health's mission to promote the health of its citizens, it practices a harm reduction model, including needle exchange, which is proven to reduce the spread of viral infections like HIV, hepatitis B and hepatitis C.[8] Since 2013, SFPDH's has made additional efforts to improve needle disposal through its coordination and funding of several collaborative and community-based programs: San Francisco Public Works provides maintenance for the streets and groundwork of San Francisco: This branch of SFDPH is part of the Quality Improvement branch that hosts multiple programs and initiatives to promote active-living, healthy eating, and decreasing the spread of STIs, such as HIV.